تعیین دقیق مقادیر S سلولی برای چشمه های تک انرژی الکترون و رادیونوکلیدهای گسیلنده بتا با استفاده از کد مونت کارلوی GEANT4

نویسندگان

1 دانشگاه صنعتی امیرکبیر

2 دانشگاه صنعتی شریف

10.22052/6.1.57

چکیده

در این مقاله، محاسبه مقادیر S با استفاده از شبیه­سازی تک سلول در کد مونت­کارلوی Geant4 ابزار Geant4-DNA برای چشمه­های تک انرژی الکترون با محدوده انرژی keV 1 تا keV 70 و برای دو رادیونوکلید گسیلنده الکترون اوژه ایندیوم-111 و تکنسیوم-m99 در آب مایع انجام گردید. مقادیر S حاصل با مقادیر داده شده توسط کمیته MIRD مقایسه و درصد تفاوت بین آن­ها محاسبه گردید. اگرچه در اکثر موارد این تفاوت کم­تر از 20 درصد تعیین شد، اما در برخی موارد تفاوت­های بیش­تری نیز مشاهده گردید. نتایج حاصل از این مقاله دارای توافق خوبی با مطالعات سایرین در این زمینه است. این پژوهش گامی مهم در جهت انجام دزیمتری در ابعاد سلولی و استفاده از نتایج آن­ها در راستای بهبود طراحی درمان در کشور می­باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Accurate determination of cellular S-values for monoenergetic electron sources and beta emitting radionuclides using Geant4-DNA Monte Carlo code

نویسندگان [English]

  • Fatemeh Fathi 1
  • Fereshte Saheli 2
  • Mojtaba Shamsaeezafarghandi 1
  • Naser Vosoghi 2
1
2
چکیده [English]

In this paper, cellular S-values for monoenergetic electron sources with energy from 1 to 70keV and the Auger-electron emitting radionuclides Tc-99m and In-111 were calculated in liquid water using the Geant4 Monte Carlo toolkit with the low energy extension Geant4-DNA. The results were compared to corresponding MIRD database and the differences were calculated. Differences between Geant4-DNA and MIRD results up to 70% were found; However, for the present monoenergetic sources and radionuclides, they mostly remain below 20%. Calculated S-values in this paper, were in good agreement to S-values obtained in the other literatures. This study is an important step for performing cellular dosimetry which the results would improve the treatment planning in the country.

کلیدواژه‌ها [English]

  • MIRD
  • Microdosimetry
  • Geant4 code
  • Geant4-DNA toolkit
  • S-values
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