برآورد دز جذبی تیروئید ناشی از پرتودرمانی سر‌ و ‌گردن در مرکز شهید رمضان زاده یزد

نویسندگان

دانشگاه علوم پزشکی شهید صدوقی یزد

10.22052/5.3.9

چکیده

در دهه‌‌های اخیر پرتو‌‌درمانی نقش اساسی در درمان انواع سرطان‌‌ها ایفا نموده است. دستیابی به کنترل تومور [1](TCP < /span>) و کاهش عارضه­های بافت سالم [2](NTCP < /span>) ایده­آل پرتودرمانی است ]1[. حساسیت غده تیروئید به پرتوها منجر به افزایش خطرسرطان ثانویه و کم‌کاری تیروئید ناشی از پرتوهای اولیه و ثانویه در پرتو‌درمانی ‌می­گردد. در این بررسی متوسط دز‌ جذبی تیروئید ناشی از رادیوتراپی تومور‌های سر و‌ گردن در بیماران ارجاعی به مرکز شهید رمضان­زاده یزد تعیین گردید. دزیمتری به روش TLD و محاسبات TPS انجام شد. نتایج حاکی از آن بود که دز ‌جذبی تیروئید ناشی از پرتوهای ثانویه در پرتودرمانی تومورهای سر ‌‌و‌ گردن به‌طور متوسط 37/4 درصد و در پرتودرمانی تمام مغز 7/0 درصد دز تجویزی و کمتر از حد آستانه تحمل تیروئید بود.
 

[1]tumor control probability

[2]normal tissue complication probability

کلیدواژه‌ها

عنوان مقاله [English]

Thyroid dose as a result of radiation therapy for head and neck malignancies in Ramezanzadeh radiotherapy center of Yazd

نویسندگان [English]

  • fathollah Bouzarjomehri
  • Samira Yazdani
  • Masoud Shabani
  • Ania Jafari
چکیده [English]

In recent decades, radiotherapy has been had a fundamental role in the treatment of cancers. The tumor control probability (TCP) and lowest risk in normal tissue is the aim of radiotherapy techniques. The radiation sensitivity of thyroid glands increases cancer risk of scattering radiation and induces hypothyroidism. In this study, the average thyroid dose due to head and neck radiotherapy in the patients referred to Ramezanzadeh radiotherapy center of Yazd was measured. Dosimetry was achieved by TLD measurement and TPS calculations methods. The results showed that the absorbed dose of thyroid in head and neck radiotherapy and in whole-brain radiotherapy were 4.37 and 0.7 percent of the prescription dose, respectively. The mean of thyroid absorbed dose was less than the tolerance threshold dose.

کلیدواژه‌ها [English]

  • Radiotherapy
  • Hypothyroidism
  • Thermolumincsencedosimetry
  • Treatment planning system
  • Head and neck malignancies

مراجع

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