Separation of 153Sm as a therapeutic radionuclide from Eu impurities using electro-amalgamation

Document Type : Original Article

Authors

1 Fouman Faculty of Technology, University of Tehran, Iran

2 Nuclear Fuel Cycle Research School, Nuclear Science and Technology Research Institute, Tehran, Iran

3 Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI), North Kargar Street, Tehran, Iran

Abstract

Given to its favorable radionuclidic characteristics, such as tl/2 = 1.93 days and Eβ(max) = 0.71 MeV and ease of its large-scale production using medium flux research reactors, 153Sm is an attractive radionuclide for various therapeutic applications. 153Sm is a beta and gamma emitter that due to its physical and radiochemical properties is ideal for the treatment of bone metastasis. In this study, 153Sm was produced by thermal neutrons irradiation of 152Sm in the Tehran research reactor with a flux of 2.5 ×1013 n / cm2.s. A two-step electrolysis was used to separate 153Sm with separation efficiency of 88.25% from europium in lithium citrate medium by optimization of voltage (6V), electrolyte concentration (0.2 M), pH (6) and time (30 min).
 

Keywords

References

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