Expansion colorimetric method to calculate the specific absorption rate of iron oxide nanoparticles, cobalt ferrite and nickel ferrite in the treatment of cancer cells through hyperthermia

Document Type : Conference Paper

Authors

Physics Department, Islamic Azad University, Shiraz, Fars, Iran

Abstract

Abnormal cell proliferation and the body's inability to resolve this problem can lead to cancer. Common methods of cancer treatment have side effects. The use of magnetic nanoparticles under a   magnetic   field is   a   promising   approach in   the treatment   of cancer.   When magnetic nanoparticles are placed in an alternating magnetic field, the fro fluid transfers heat energy and reaches equilibrium.  The effective mechanisms  for  generating  heat  in  hypothermia are  Neel's and  Brownian's relaxation. The specific absorption rate is one of the most important parameters in the design of magnetic nanoparticles for heat therapy. At present, the calorimetric method is used to determine the specific absorption rate of nanoparticles. Tumor warming can cause serious damage to surrounding healthy cells. On the other hand, if the temperature rise is not high enough, the desired treatment can not be achieved. In this paper, we have used a colorimetric method to measure the specific adsorption rate for three nanoparticles of Fe3O4, NiFe2O4, and CoFe2O4.

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