Physics Department, University of Guilan, Rasht, Guilan, Iran
Abstract
Nowadays, with the advancement of nano-technology, nanoparticles with high atomic number can be concentrated in tumor cells. The presence of nanoparticles within the tumor causes an increase in the tumor sensitivity to the radiation while healthy tissues nearby get the least damage. In the present study, using the code mcnpx, phantom consisting of a cube with sides of 10 cm containing soft tissue and a tumor with sides of 0.5 cm were considered. In order to investigate the effect of nanoparticles with radius 15, 50 and 100 were used. The results showed that the optimum energy in the presence of nanoparticles with radius 15 and 50
H. Khosravi, B. Hashemi, S.Mahdavi, P. Hejazi, H. Mandar, Target dose enhancement factor alterations related to interaction between the photon beam energy and goldnanoparticles’ size in external radiotherapy: using Monte Carlo method. Koomesh. Meas. 17 (1) (2015) 255-261.
R. Lévy, N. T. K. Thanh, R C. Doty, I. Hussain, R. J. Nichols, D. J. Schiffrin, M. Brust, D. G. Fernig. Rational and combinatorial design of peptide capping ligands for gold nanoparticles. J. Am. Chem. Soc. (2004) 10076-10084.
X. D. Zhang, M. L. Guo, H. Y. Wu, Y. M. Sun, Y. Q. Ding, X. Feng, L. A. Zhang. Irradiation stability and cytotoxicity of gold nanoparticles for radiotherapy. Int. J. Nanomedicine. 4 (2009) 165-173.
X. Zhang, J. Z. Xing, J. Chen, L. Ko, J. Amanie, S. Gulavita, N. Pervez, D. Yee, R. Moore, W. Roa. Enhanced radiation sensitivity in prostate cancer by gold-nanoparticles. Clin. Invest. Med. 31 (3) (2008) E160-7.
X. Zhang, J. Gao, T.A. Buchholz, Z. Wang, M. R. Salehpour, R. A. Drezek, T. -K. Yu. Quantifying tumor-selective dose enhancement using gold nanoparticles: a monte carlo simulation study. Biomed Microdevices 11 (4) (2009) 925-933.
J. F. Hainfeld, D. N. Slatkin, H. M. Smilowitz. The use of gold nanoparticles to enhance radiotherapy in mice. Phys. Med. Biol. (2004) 49 (18) 309-15.
Sadremomtaz, A., & Dalili, N. (2023). Effect of the radius of the gold nanoparticles on the range of secondary particles has been produced in energy ranges of K and L edges. Journal of Radiation Safety and Measurement, 11(5), 213-217.
MLA
Alireza Sadremomtaz; Narjess Dalili. "Effect of the radius of the gold nanoparticles on the range of secondary particles has been produced in energy ranges of K and L edges". Journal of Radiation Safety and Measurement, 11, 5, 2023, 213-217.
HARVARD
Sadremomtaz, A., Dalili, N. (2023). 'Effect of the radius of the gold nanoparticles on the range of secondary particles has been produced in energy ranges of K and L edges', Journal of Radiation Safety and Measurement, 11(5), pp. 213-217.
VANCOUVER
Sadremomtaz, A., Dalili, N. Effect of the radius of the gold nanoparticles on the range of secondary particles has been produced in energy ranges of K and L edges. Journal of Radiation Safety and Measurement, 2023; 11(5): 213-217.
)