Journal of Radiation Safety and Measurement

Journal of Radiation Safety and Measurement

deep dose calculated in the production of 18F radioisotope in water target collision with plasma focus device

Document Type : Conference Paper

Authors
Hiva Rokhzadi Zardouei 1
Mostafa Hasanzadeh 2
Abdolah Refaei 1
Seyed Mahmood Sadatkiaei 3
1 Department of physics, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
2 Reactor and Nuclear Safety Research School, Nuclear Science and Technology Research Institute (NSTRI), AEOI, Tehran, Iran
3 Plasma and Nuclear Fusion Research School, Nuclear Science and Technology Research Institute (NSTRI), AEOI, Tehran, Iran
Abstract
One of the reasons for the use of PET radioisotopes in medical research is the presence of a series of positron emitters such as 11C, 13N, 15O, and 18F. The detectors combined with them perform a series of processes similar to natural processes in the body. Another advantage of this method is imaging of metabolic function, which causes early detection of dangerous diseases such as cancerous tumors, cardiovascular diseases, neurological diseases such as epilepsy, Parkinson's disease, and allows the doctor to treat the disease before it develops. In this research, in search of radioisotope production devices with short half-lives, to simulate the depth dose received by a phantom cube of water geometries are 20 cm at a distance of 50 cm from the spring and firing one million photons from a point spring with the energy of 25 MeV Cylindrical water with a radius of 7 cm and a height of 3 mm in order to produce radioisotope F18, Geant tool 4.10.7 has been used and to have safe radiotherapy, the received deep dose has been calculated with appropriate results.
Keywords
Radioisotope
Plasma focus
Geant 4 Simulation
Deep Dose
Positron Emitter
  1. P. Munro, J. A. Rawlinson, A. Fenster. Therapy imaging: Source sizes of radiotherapy beams. Med. Phys. 15 (1988) 517‑24.
  2. W. R. Lutz, N. Maleki, B. E. Bjärngard. Evaluation of a beam‑spot camerafor megavoltage xrays. Med. Phys. 15 (1988) 614‑7.
  3. E. Loewinger, E. Bar‑Avraham, G. Barnea. Measurement of the source size of a 6‑.and 18‑MV radiotherapy linac. Med. Phys. 19 (1992) 687‑90.
  4. D. A. Jaffray, J. J. Battista, A. Fenster, P. Munro. X‑ray sources of medical linear accelerators: Focal and extra‑focal radiation. Med. Phys. 20 (1993) 1417‑27.
  5. A. E. Schach von Wittenau, C. M. Logan, R. D. Rikard. Using a tungsten rollbar to characterize the source spot of a megavoltage bremsstrahlunglinac. Med. Phys. 29 (8) (2002) 1797‑806.
  6. H. H. Liu, T. R. Mackie, E. C. McCullough. A dual source photon beam model used in convolution/ superposition dose calculations for clinical megavoltage x‑ray beams. Med. Phys. 24 (1997) 1960‑74.
  7. C. L. Hartmann Siantar, R. S. Walling, T. P. Daly, B. Faddegon, N. Albright, P. Bergstrom, A. F. Bielajew, C. Chuang, D. Garrett, R. K. House, D. Knapp, D. J. Wieczorek, L. J. Verhey. Description and dosimetric verification of the PEREGRINE Monte Carlo dose calculation system for photon beams incident on a water phantom. Med. Phys. 28 (2001) 1322‑37.
  8. B. Bieńkowska, S. Jednoróg, I. M. Ivanova-Stanik, M. Scholz, A. Szydłowski. Application of the ion beam emitted from plasma focus device for target activation. Acta Phys. Slovaca 54 (4) (2004) 401-407.
  9. C. Bohlken, et al. Production of [18F] from [18F]-Fluoride Using A Plasma Induced Scrambling Procedure. (GE Healthcare, Inc. IP Department 101 Carnegie Cente, Princeton NJ, 08540, US) WIPO Patent Application WO/2007/129165.
  10. M. Frignani, S. Mannucci, D. Mostacci, F. Rocchi, M Sumini, L. Karpinski. Short circuit tests on a 150 kJ, 1 hz repetitive Plasma Focus. Czech. J. Phys. (Suppl 2) 56 (2006) B413-B418.