Department of Physics, Faculty of Basic Sciences, Imam Khomeini International University, Qazvin, Iran
Abstract
In this project, feasibility of direct production of praseodymium-140 radioisotope by direct method using 140Ce(p,n)140Pr reaction excitation function obtained from the calculation code TALYS-1.8 has been investigated. On the other hand, due to the short half-life 3.39m, this radioisotope can be produced in small portable cyclotron to medical centers. Using the excitation function, the optimal energy range for the proton projectile to achieve the maximum product cross-section 140Pr and the minimum isotopic and non-isotopic contamination caused by other decay channels during the reaction, it is determined. Finally, the theoretical production yield is compared with the simulated production yield, which are directly and indirectly derived from the MCNPX code.
S. K. Zeisler, D. W. Becker. A new method for PET imaging of tumours: human serum albumin labeled with the long-lived Nd-140/Pr-1410 in vivo radionuclide generator. Clin. Positron Imaging 2 (6) (1999) 324.
D. Nayak, S. Lahiri. Application of radioisotopes in the field of nuclear medicine. J. Radioanal. Nucl. Chem. 242 (1999) 423-432.
M. Sadeghy, A. Ghanbarzade, M. Enferadi. Nuclear data for cyclotron prodaction of 140 Nd/140Pr used in gamma camera monitoring, RIT, ERT and PET. Kerntechnik 75 (6) (2010) 363-368.
A. J. Koning, S. Hilaire, M. C. Duijvestijn, TALYS-1.0. in Proceedings of the International Conference on Nuclear Data for Science and Technology – ND2007, (EDP Sciences Volume 1, eds. O. Bersillon, F. Gunsing, E. Bauge, R. Jacqmin and S. Leray, Apr. 22–27, 2007, Nice, France, 2008) pp. 211-214.
J. F. Ziegler, M. D. Ziegler, J. P. Biersack, Nucl. Instrum. Meth. Phys. Res., Sect. B 268 (2010) 1818.
J. S. Hendricks, G. W. McKinney, M. L. Fensin, M. R. James, R. C. Johns, J. W. Durkee, J. P. Finch, D. B. Pelowitz, L. S. Waters, M. W. Johnson. MCNPX2.6.0 Extensions LA-UR-08-2216-Los Alamos National laboratory, 2008.
Ashori, S., & Kakavand, T. (2023). Simulation of radioisotope production of Praseodymium-140 by Monte Carlo method. Journal of Radiation Safety and Measurement, 11(5), 117-120.
MLA
Sanaz Ashori; Tayeb Kakavand. "Simulation of radioisotope production of Praseodymium-140 by Monte Carlo method", Journal of Radiation Safety and Measurement, 11, 5, 2023, 117-120.
HARVARD
Ashori, S., Kakavand, T. (2023). 'Simulation of radioisotope production of Praseodymium-140 by Monte Carlo method', Journal of Radiation Safety and Measurement, 11(5), pp. 117-120.
VANCOUVER
Ashori, S., Kakavand, T. Simulation of radioisotope production of Praseodymium-140 by Monte Carlo method. Journal of Radiation Safety and Measurement, 2023; 11(5): 117-120.