Zero dimensional model for determining particle and energy densities of P-11B fusion reaction in radiotherapy

Authors

10.22052/8.1.7

Abstract

Three alpha particles are emitted from the P-11B fusion reaction. Alpha particles play an important role in the death of cancer cells. When boron is accumulated in the tumor, protons irradiated out of body can react with the boron in the tumor. Also a fast gamma ray of 719 KeV beam is released from the P-11B fusion reaction which plays a useful role for us. This therapeutic approach includes features and benefits such as the application of Bragg Peak in treatment, precise targeting of the tumor, increased therapeutic effect, and observation and monitoring of the treatment area.
 

Keywords


[1] C. Labaune, C. Baccou, S. Depierreux, C. Goyon, G. Loisel, V. Yahia, and J. Rafelski. Fusion Reactions Initiated by Laser-Accelerated Particle Beams in a Laser-Produced Plasma, Nature Communications, 4 (2506) (2013). [2] J.M. Martinez-Val, S. Eliezer, M. Piera, and G. Velarde. Fusion Burning Waves in Proton-Boron-11 Plasmas, Phys. Lett. A 216(1-5) (1996) 142–152. [3] D. C. Moreau. Potentiality of the Proton-Boron Fuel for Controlled Thermonuclear Fusion, Nuclear Fusion 17(1) (1977) 13–20. [4] B. Levush and S. Cuperman. On the Potentiality of the Proton-Boron Fuel for Inertially Confined Fusion, Nuclear Fusion 22(11) (1982) 1519–1525. [5] T. Kobayashi, Y. Sakurai, and M. Ishikawa. A Noninvasive Dose Estimation System for Clinical BNCT Based on PG‐SPECT—Conceptual Study and Fundamental Experiments Using HPGe and CdTe Semiconductor Detectors, Med. Phys. 27(9) (2000) 2124–2132. [6] Do-Kun Yoon, Joo-Young Jung, and Tae Suk Suha. Application of Proton Boron Fusion Reaction to Radiation Therapy: A Monte Carlo simulation study, APPLIED PHYSICS LETTERS 105(223507) (2014). [7] M.J. Berger and S.M. Seltzer. ETRAN. Monte Carlo Code Sys-tem for Electron and Photon Transport Through Extended Media, ORNL Documentation for RSIC Computer Code Package CCC-107 (1973). [8] J.F. Breismeister. MCNPTM –A general Monte Carlo N–particle Transport Code. Version 4C Manual LA-13709-M (2000) 1–790. [9] F. Salvat, J.M. Fernadez-Varea, E. Acosta and J. Sempaul. PENELOPE-A Code System for Monte Carlo Simulation of Electron and Photon Transport. Nuclear Science Committee. Nuclear Energy Agency Organisation For Economic Co-Operation And Development (2001)1–248. [10] W.R. Nelson, H. Hirayama and DWO. Rogers. The EGS4 Code System. Rapport SLAC-265. Standard Linear Accelerator Center, (Standford, Californie) (1985) 1–206. [11] A. Badano and J. Sempau. MANTIS: Combined x-ray, Electron and Optical Monte Carlo Simulations of Indirect Radiation Imaging Systems, Physics in Medicine and Biology 51(6) (2006) 1545–1561. [12] A. Ferrari. Fluka: A Multi-Particle Transport Code, Geneva CERN (2005). [13] Geant4 User's Guide for Application Developers. V.GEANT4 6.1. Application Developers Guide (2004) 1–221.