Determination of intensity and energy spectrum of neutrons during the production of radiopharmaceutical FDG

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10.22052/4.2.39

Abstract

Neutron spectrum and intensity that produced from H218O target bombardment were determined. SRIM and ALICE computer codes were applied to H218O target and its Titanium window for 17 MeV incident proton beam from cyclotron Cyclone30. Using calculated neutron intensity and spectrum as the source, equivalent dose rate at a certain distance from the target was calculated by the MCNP computer code and compared with the measured value.

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References

[1] International Atomic Energy Agency.Charged Particle Crosss-Section Database for Medical Radioisotope Production: diagnostic radioisotopes and monitor reactions. Report IAEA-TECDOC-1211 (2001). [2] J. F. Ziegler and J. P. Biersack.SRIM (2003).http://www.SRIM.org. [3] M.Blann ,J.Bisplinghoff. Code ALICE / Livermore 82. Report UCID-19614. Lawrence Livermore National Laboratory.CA (1982). [4] A.Bosko. General Electric Pettrace Cyclotron as A Neutron Source For Boron Neutron Capture Therapy. Texas University, (2005) 54. [5] J. F. Briesmeister, editor. MCNP-4C A General Monte Carlo N-Particle Transport Code System-Version 4C.Los Alamos National Laboratory, LA-13709-M (2000). [6] EG&G Berthold. Operating Manual Neutron Probe LB6411. Id. No. 1-20188-82042 BA2 Rev. No. 01. (1996).

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